Spironolactone has antiandrogenic activity. As such in cases of patient concern or persistent virilized features in the presence of a female-range total testosterone, calculation of the bioavailable testosterone may help fine tune hormone regimens for optimal effect. Serum hormone levels after 6 months of treatment with different doses of conjugated equine estrogen alone or with cyproterone acetate in transgender women. Our results demonstrated that the different doses of CEE 0. Transdermal preparation is the safest form of estrogen administration, especially in transsexual patients who smoke or have diabetes because the transdermal preparation does not influence protein, lipoprotein or triglyceride synthesis, thereby reducing the thrombotic and cardiovascular risks 3. Androvax androstenedione albumin Ovandrotone albumin Fecundin.
Danazol Gestrinone Progestins e.
Adapalene Isotretinoin Motretinide Tazarotene Tretinoin. United States Food and Drug Administration. Conversely, Endocrine Society guidelines recommend monitoring of hormone levels every 3 months. Brittain 26 November It is reasonable check both total and bioavailable testosterone levels, and consider reduction of androgen blockade to allow an increase in testosterone, depending on patient goals. Orentreich N, Durr NP. Patients with a history of migraines should consider starting with a low dose and titrating upward as tolerated.
Expert Opin Investig Drugs. Many transgender women may be unable or unwilling to quit smoking; this should not represent an absolute contraindication to estrogen therapy. Due to the risks of serious side effects, the lowest possible dose of estrogen is used  . Patients with a history of migraines should consider starting with a low dose and titrating upward as tolerated. Feminizing hormone therapy will begin producing changes in your body within weeks to months.